G2E3 Is a Dual Function Ubiquitin Ligase Required for Early Embryonic Development

G2E3 is a putative ubiquitin ligase (E3) identified in a microarray screen for mitotic regulatory proteins. It shuttles between the cytoplasm and nucleus, concentrating in nucleoli and relocalizing to the nucleoplasm in response to DNA damage. In this study, we demonstrate that G2E3 is an unusual ub...

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Bibliographische Detailangaben
Hauptverfasser: Brooks, William S., Helton, E. Scott, Banerjee, Sami, Venable, Melanie, Johnson, Larry, Schoeb, Trenton R., Kesterson, Robert A., Crawford, David F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Molecular Basis of Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494922/
https://ncbi.nlm.nih.gov/pubmed/18511420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803238200
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