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Covalent Binding to Tubulin by Isothiocyanates: A MECHANISM OF CELL GROWTH ARREST AND APOPTOSIS
Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC), phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models and induce apoptosis and cell cycle arrest in various cell types. The biochemical mechanisms of cell growth inhibition by ITCs a...
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Główni autorzy: | , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Biochemistry and Molecular Biology
2008
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494917/ https://ncbi.nlm.nih.gov/pubmed/18524779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802330200 |
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