Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, αvβ(3)-integrin, and TGF-β1 in response to ANG II and high glucose

This study determines that vascular smooth muscle cell (VSMC) signaling through extracellular signal-regulated kinase (ERK) 1/2-mitogen-activated protein (MAP) kinase, αvβ(3)-integrin, and transforming growth factor (TGF)-β1 dictates collagen type I network induction in mesenteric resistance arterie...

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Detalhes bibliográficos
Main Authors: Belmadani, Souad, Zerfaoui, Mourad, Boulares, Hamid A., Palen, Desiree I., Matrougui, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494762/
https://ncbi.nlm.nih.gov/pubmed/18456735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00341.2008
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