Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats

Vascular superoxide anion (O(2)(•−)) levels are increased in DOCA-salt hypertensive rats. We hypothesized that the endothelin (ET)-1-induced generation of ROS in the aorta and resistance arteries of DOCA-salt rats originates partly from xanthine oxidase (XO) and mitochondria. Accordingly, we blocked...

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Detaylı Bibliyografya
Asıl Yazarlar: Viel, Emilie C., Benkirane, Karim, Javeshghani, Danesh, Touyz, Rhian M., Schiffrin, Ernesto L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2008
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494748/
https://ncbi.nlm.nih.gov/pubmed/18487445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00304.2008
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