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Mechanism of leukotriene D(4) inhibition of Na-alanine cotransport in intestinal epithelial cells

In a rabbit model of chronic intestinal inflammation, we previously demonstrated inhibition of neutral Na-amino acid cotransport. The mechanism of the inhibition was secondary to a decrease in the affinity for amino acid rather than the number of cotransporters. Since leukotriene (LT)D(4) is known t...

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Autors principals: Talukder, Jamilur R., Kekuda, Ramesh, Saha, Prosenjit, Sundaram, Uma
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494717/
https://ncbi.nlm.nih.gov/pubmed/18436626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00498.2007
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