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Response of the flat cochlear epithelium to forced expression of Atoh1

Following hair cell elimination in severely traumatized cochleae, differentiated supporting cells are often replaced by a simple epithelium with cuboidal or flat appearance. Atoh1 (previously Math1) is a basic helix-loop-helix transcription factor critical to hair cell differentiation during mammali...

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Autores principales: Izumikawa, Masahiko, Batts, Shelley A., Miyazawa, Toru, Swiderski, Donald L., Raphael, Yehoash
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494705/
https://ncbi.nlm.nih.gov/pubmed/18430530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2008.02.007
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