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Identification of downstream genetic pathways of Tbx1 in the second heart field
Tbx1, a T-box transcription factor, and an important gene for velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) in humans, causes outflow tract (OFT) heart defects when inactivated in the mouse. Tbx1 is expressed in the second heart field (SHF) and is required in this tissue for OFT developme...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494702/ https://ncbi.nlm.nih.gov/pubmed/18328475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.01.037 |
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