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Identification of downstream genetic pathways of Tbx1 in the second heart field

Tbx1, a T-box transcription factor, and an important gene for velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) in humans, causes outflow tract (OFT) heart defects when inactivated in the mouse. Tbx1 is expressed in the second heart field (SHF) and is required in this tissue for OFT developme...

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Autori principali: Liao, Jun, Aggarwal, Vimla S., Nowotschin, Sonja, Bondarev, Alexei, Lipner, Shari, Morrow, Bernice E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494702/
https://ncbi.nlm.nih.gov/pubmed/18328475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.01.037
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