Protein Kinase C-δ Mediates Neuronal Apoptosis in the Retinas of Diabetic Rats via the Akt Signaling Pathway

OBJECTIVE—Protein kinase C (PKC)-δ, an upstream regulator of the Akt survival pathway, contributes to cellular dysfunction in the pathogenesis of diabetes. Herein, we examined the role of PKC-δ in neuronal apoptosis through Akt in the retinas of diabetic rats. RESEARCH DESIGN AND METHODS—We used ret...

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Autores principales: Kim, Young-Hee, Kim, Yoon-Sook, Park, Chang-Hwan, Chung, In-Yong, Yoo, Ji-Myong, Kim, Jae-Geun, Lee, Byung-Ju, Kang, Sang-Soo, Cho, Gyeong-Jae, Choi, Wan-Sung
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2008
Materias:
Complications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494683/
https://ncbi.nlm.nih.gov/pubmed/18443201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1431
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