Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin
The presence of endotoxin from Gram-negative bacteria signals the innate immune system to up-regulate bacterial clearance and/or killing mechanisms. Paradoxically, such responses also contribute to septic shock, a clinical problem occurring with high frequency in Gram-negative septicemia. CD14 is a...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811894/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13875 |
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