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Phytohemagglutinin-induced activity of cyclic AMP (cAMP) response elements from cytomegalovirus is reduced by cyclosporine and synergistically enhanced by cAMP.

The 19-base-pair enhancer repeat of the human cytomegalovirus immediate-early 1 gene mediates cyclic AMP- and phytohemagglutinin-induced expression in Jurkat T cells. Synergistic activity was observed in the presence of both drugs, suggesting a convergence of the protein kinase A and C pathways on t...

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Vydáno v:J Virol
Hlavní autoři: Niller, H H, Hennighausen, L
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.2388-2391.1990
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