Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNA.

Interaction between the trans-acting DNA-binding protein EBNA-1 and cis-acting sequences in the ori-P region of Epstein-Barr virus DNA is required for maintenance of the viral plasmid state in latently infected B cells and is involved in the regulation of transcription during latency. In the Epstein...

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Udgivet i:J Virol
Main Authors: Ambinder, R F, Shah, W A, Rawlins, D R, Hayward, G S, Hayward, S D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249398/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157891/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.2369-2379.1990
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