Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice

Duchenne Muscular Dystrophy is a genetic disease caused by the lack of the protein dystrophin. Dystrophic muscles are highly susceptible to contraction-induced injury, and following contractile activity, have disrupted plasma membranes that allow leakage of calcium ions into muscle fibers. Because o...

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Hlavní autoři: Ng, Rainer, Metzger, Joseph M., Claflin, Dennis R., Faulkner, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
Muscle Cell Biology and Cell Motility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493563/
https://ncbi.nlm.nih.gov/pubmed/18495816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00017.2008
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