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Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy
Angiopoietins were thought to be endothelial cell-specific via the tie2 receptor. We showed that angiopoietin-1 (ang1) also interacts with integrins on cardiac myocytes (CMs) to increase survival. Because ang1 monomers bind and activate integrins (not tie2), we determined their function in vivo. We...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Federation of American Societies for Experimental Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493452/ https://ncbi.nlm.nih.gov/pubmed/18502941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-100966 |
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