Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

Genomic imprinting is a developmentally important mechanism that involves both differential DNA methylation and allelic histone modifications. Through detailed comparative characterization, a large imprinted domain mapping to chromosome 7q21 in humans and proximal chromosome 6 in mice was redefined....

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Detalhes bibliográficos
Main Authors: Monk, David, Wagschal, Alexandre, Arnaud, Philippe, Müller, Pari-Sima, Parker-Katiraee, Layla, Bourc’his, Déborah, Scherer, Stephen W., Feil, Robert, Stanier, Philip, Moore, Gudrun E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493428/
https://ncbi.nlm.nih.gov/pubmed/18480470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.077115.108
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