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Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals
We introduce a simple, broadly applicable method for obtaining estimates of nucleotide diversity θ from genomic shotgun sequencing data. The method takes into account the special nature of these data: random sampling of genomic segments from one or more individuals and a relatively high error rate f...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493391/ https://ncbi.nlm.nih.gov/pubmed/18411405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.074187.107 |
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