Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals

We introduce a simple, broadly applicable method for obtaining estimates of nucleotide diversity θ from genomic shotgun sequencing data. The method takes into account the special nature of these data: random sampling of genomic segments from one or more individuals and a relatively high error rate f...

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Main Authors: Hellmann, Ines, Mang, Yuan, Gu, Zhiping, Li, Peter, de la Vega, Francisco M., Clark, Andrew G., Nielsen, Rasmus
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2008
Teme:
Letter
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493391/
https://ncbi.nlm.nih.gov/pubmed/18411405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.074187.107
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