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How a Cytokine Is Chaperoned through the Secretory Pathway by Complexing with Its Own Receptor: Lessons from Interleukin-15 (IL-15)/IL-15 Receptor α

While it is well appreciated that receptors for secreted cytokines transmit ligand-induced signals, little is known about additional roles for cytokine receptor components in the control of ligand transport and secretion. Here, we show that interleukin-15 (IL-15) translocation into the endoplasmic r...

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Autors principals: Duitman, Erwin H., Orinska, Zane, Bulanova, Elena, Paus, Ralf, Bulfone-Paus, Silvia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493373/
https://ncbi.nlm.nih.gov/pubmed/18505820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02178-07
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