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The Headpiece Domain of Dematin Regulates Cell Shape, Motility, and Wound Healing by Modulating RhoA Activation

RhoA is known to participate in cytoskeletal remodeling events through several signaling pathways, yet the precise mechanism of its activation remains unknown. Here, we provide the first evidence that dematin functions upstream of RhoA and regulates its activation. Primary mouse embryonic fibroblast...

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Detalhes bibliográficos
Main Authors: Mohseni, Morvarid, Chishti, Athar H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493358/
https://ncbi.nlm.nih.gov/pubmed/18505823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00237-08
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