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The Headpiece Domain of Dematin Regulates Cell Shape, Motility, and Wound Healing by Modulating RhoA Activation

RhoA is known to participate in cytoskeletal remodeling events through several signaling pathways, yet the precise mechanism of its activation remains unknown. Here, we provide the first evidence that dematin functions upstream of RhoA and regulates its activation. Primary mouse embryonic fibroblast...

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Autors principals: Mohseni, Morvarid, Chishti, Athar H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493358/
https://ncbi.nlm.nih.gov/pubmed/18505823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00237-08
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