Differences in Hepatitis C Virus (HCV)-Specific CD8 T-Cell Phenotype during Pegylated Alpha Interferon and Ribavirin Treatment Are Related to Response to Antiviral Therapy in Patients Chronically Infected with HCV

CD8 T cells play a major role in antiviral immune responses. Their importance for progression to chronic hepatitis C and response to treatment are still unclear. To address these issues, hepatitis C virus (HCV)-specific CD8 T-cell responses were monitored, at the single-cell level, using HLA class I...

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Detalhes bibliográficos
Main Authors: Caetano, Joana, Martinho, António, Paiva, Artur, Pais, Beatriz, Valente, Cristina, Luxo, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493325/
https://ncbi.nlm.nih.gov/pubmed/18480446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02175-07
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