Differential Gene Regulation by Epstein-Barr Virus Type 1 and Type 2 EBNA2

A transfection assay with a lymphoblastoid cell line infected with Epstein-Barr virus was used to compare the abilities of type 1 and type 2 EBNA2 to sustain cell proliferation. The reduced proliferation in cells expressing type 2 EBNA2 correlated with loss of expression of some cell genes that are...

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Bibliographic Details
Main Authors: Lucchesi, Walter, Brady, Gareth, Dittrich-Breiholz, Oliver, Kracht, Michael, Russ, Rainer, Farrell, Paul J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493322/
https://ncbi.nlm.nih.gov/pubmed/18480445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00223-08
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