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Dimerization of the Papillomavirus E2 Protein Is Required for Efficient Mitotic Chromosome Association and Brd4 Binding

The E2 proteins of several papillomaviruses link the viral genome to mitotic chromosomes to ensure retention and the efficient partitioning of genomes into daughter cells following cell division. Bovine papillomavirus type 1 E2 binds to chromosomes in a complex with Brd4, a cellular bromodomain prot...

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Main Authors: Cardenas-Mora, Juan, Spindler, Jonathan E., Jang, Moon Kyoo, McBride, Alison A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493320/
https://ncbi.nlm.nih.gov/pubmed/18495759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00772-08
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