The Fibrinogen- and Fibronectin-Binding Domains of Staphylococcus aureus Fibronectin-Binding Protein A Synergistically Promote Endothelial Invasion and Experimental Endocarditis

Staphylococcus aureus experimental endocarditis relies on sequential fibrinogen binding (for valve colonization) and fibronectin binding (for endothelial invasion) conferred by peptidoglycan-attached adhesins. Fibronectin-binding protein A (FnBPA) reconciles these two properties—as well as elastin b...

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Bibliografische gegevens
Hoofdauteurs: Piroth, Lionel, Que, Yok-Ai, Widmer, Eleonora, Panchaud, Alexandre, Piu, Stéphane, Entenza, José M., Moreillon, Philippe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
Onderwerpen:
Bacterial Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493224/
https://ncbi.nlm.nih.gov/pubmed/18541660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00405-08
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