Short tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2

CXCR2 plays an important role during cutaneous wound healing. Transgenic mice were generated using the keratin-14 promoter/enhancer to direct expression of wild-type human CXCR2 (K14hCXCR2 WT) or mutant CXCR2, in which the carboxyl-terminal domain (CTD) was truncated at Ser 331 and the dileucine AP-...

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Главные авторы: Yu, Yingchun, Su, Yingjun, Opalenik, Susan R., Sobolik-Delmaire, Tammy, Neel, Nicole F., Zaja-Milatovic, Snjezana, Short, Sarah T., Sai, Jiqing, Richmond, Ann
Формат: Artigo
Язык:Inglês
Опубликовано: The Society for Leukocyte Biology 2008
Предметы:
Pathogenesis and Host Defense
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493076/
https://ncbi.nlm.nih.gov/pubmed/18505935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0807544
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