Anthrax Toxins Inhibit Neutrophil Signaling Pathways in Brain Endothelium and Contribute to the Pathogenesis of Meningitis

BACKGROUND: Anthrax meningitis is the main neurological complication of systemic infection with Bacillus anthracis approaching 100% mortality. The presence of bacilli in brain autopsies indicates that vegetative bacteria are able to breach the blood-brain barrier (BBB). The BBB represents not only a...

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Detalhes bibliográficos
Main Authors: van Sorge, Nina M., Ebrahimi, Celia M., McGillivray, Shauna M., Quach, Darin, Sabet, Mojgan, Guiney, Donald G., Doran, Kelly S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493037/
https://ncbi.nlm.nih.gov/pubmed/18698416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002964
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