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Contribution of the M(3) muscarinic receptors to the vasodilator response to acetylcholine in the human forearm vascular bed

AIMS: Acetylcholine (ACh) is a muscarinic agonist that causes receptor-mediated, endothelium-dependent vasodilatation in the forearm vasculature. Previous indirect evidence suggests this effect may be mediated by muscarinic M(3) receptors. Darifenacin is a recently developed antimuscarinic drug with...

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Bibliographic Details
Main Authors: Attinà, Teresa M, Oliver, James J, Malatino, Lorenzo S, Webb, David J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492922/
https://ncbi.nlm.nih.gov/pubmed/18489612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03194.x
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