The reproducibility of adenosine monophosphate bronchial challenges in mild, steroid-naive asthmatics

AIMS: Repeated adenosine monophosphate (AMP) challenges are used to assess drug efficacy in clinical trials of mild, steroid-naive asthmatics. Refractoriness has been reported after repeated challenges over short intervals. This study evaluated possible tachyphylaxis after repeated AMP challenges at...

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Bibliographic Details
Main Authors: Singh, Dave, Fairwood, Jennifer, Murdoch, Robert, Weeks, Amanda, Russell, Paul, Roy, Kay, Langley, Steve, Woodcock, Ashley
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Methods in Clinical Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492916/
https://ncbi.nlm.nih.gov/pubmed/18507658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03186.x
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