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Viral vector-mediated blockade of the endocrine stress-response modulates non-spatial memory
Stress results in the release of glucocorticoids (GCs) which, at high levels, impair hippocampus-dependent tasks. Estrogen is neurotrophic and can rescue stress-induced memory impairments. Here we report the use of a viral-vector to overexpress a chimeric gene (ER/GR) that converts the deleterious e...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492835/ https://ncbi.nlm.nih.gov/pubmed/18423865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.03.016 |
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