A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle

Myogenin is the dominant transcriptional regulator of embryonic and fetal muscle differentiation and during maturation is profoundly down-regulated. We show that a highly conserved 17-bp DNA cis-acting sequence element located upstream of the myogenin promoter (myogHCE) is essential for postnatal re...

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Hauptverfasser: Berghella, Libera, De Angelis, Luciana, De Buysscher, Tristan, Mortazavi, Ali, Biressi, Stefano, Forcales, Sonia V., Sirabella, Dario, Cossu, Giulio, Wold, Barbara J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492748/
https://ncbi.nlm.nih.gov/pubmed/18676817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.468508
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