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Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3

The recent discovery of H3K27me3 demethylases suggests that H3K27me3 may dynamically regulate gene expression, but this potential role in mammalian tissue homeostasis remains uncharacterized. In the epidermis, a tissue that balances stem cell self-renewal with differentiation, H3K27me3, occupies the...

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Hlavní autoři: Sen, George L., Webster, Daniel E., Barragan, Deborah I., Chang, Howard Y., Khavari, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492733/
https://ncbi.nlm.nih.gov/pubmed/18628393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1673508
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