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Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development

Phospholipid hydroperoxide glutathione peroxidase (GPx4) is a moonlighting selenoprotein, which has been implicated in basic cell functions such as anti-oxidative defense, apoptosis, and gene expression regulation. GPx4-null mice die in utero at midgestation, and developmental retardation of the bra...

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Detalhes bibliográficos
Main Authors: Ufer, Christoph, Wang, Chi Chiu, Fähling, Michael, Schiebel, Heike, Thiele, Bernd J., Billett, E. Ellen, Kuhn, Hartmut, Borchert, Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492670/
https://ncbi.nlm.nih.gov/pubmed/18593884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.466308
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