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Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses

The B7 family member B7-H3 (CD276) plays important roles in immune responses. However, the function of B7-H3 remains controversial. We found that murine B7-H3 specifically bound to Triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2, TREML2). TLT-2 was expressed on CD8(+)...

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Detalhes bibliográficos
Main Authors: Hashiguchi, Masaaki, Kobori, Hiroko, Ritprajak, Patcharee, Kamimura, Yosuke, Kozono, Haruo, Azuma, Miyuki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492502/
https://ncbi.nlm.nih.gov/pubmed/18650384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802423105
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