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High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage

High mobility group protein B1 (HMGB1) is a multifunctional protein with roles in chromatin structure, transcriptional regulation, V(D)J recombination, and inflammation. HMGB1 also binds to and bends damaged DNA, but the biological consequence of this interaction is not clearly understood. We have s...

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Библиографические подробности
Главные авторы: Lange, Sabine S., Mitchell, David L., Vasquez, Karen M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492475/
https://ncbi.nlm.nih.gov/pubmed/18650382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803181105
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