Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen.

The C gene of hepatitis B virus (HBV) codes for a nucleocapsid protein made of 183 amino acid residues and is preceded in phase by the precore (pre-C) region, encoding 29 residues. The pre-C-region product is required for the synthesis and secretion of hepatitis B e antigen (HBeAg), which is made of...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Okamoto, H, Yotsumoto, S, Akahane, Y, Yamanaka, T, Miyazaki, Y, Sugai, Y, Tsuda, F, Tanaka, T, Miyakawa, Y, Mayumi, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1298-1303.1990
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