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Molecular basis for linkage of a continuous and discontinuous neutralization epitope on the structural polypeptide VP2 of poliovirus type 1.

We obtained neutralizing monoclonal antibodies against a continuous neutralization epitope on VP2 of poliovirus type 1 strain Mahoney by using a combined in vivo-in vitro immunization procedure. The antibody-binding site was mapped to amino acid residues within the peptide segment (residues 164 thro...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Wiegers, K J, Wetz, K, Dernick, R
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1990
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1689392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1283-1289.1990
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