Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter.

The human protein p78 is induced and accumulated in cells treated with type I interferon or with some viruses. It is the human homolog of the mouse Mx protein involved in resistance to influenza virus. A full-length cDNA clone encoding the human p78 protein was cloned and sequenced. It contained an...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Horisberger, M A, McMaster, G K, Zeller, H, Wathelet, M G, Dellis, J, Content, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1171-1181.1990
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