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The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions.

The BZLF1 or zta immediate-early gene of Epstein-Barr virus (EBV) encodes a 33-kilodalton phosphorylated nuclear protein that is a specific transcriptional activator of the EBV lytic cycle when introduced into latently infected B lymphocytes. We have shown previously that the divergent EBV DSL targe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lieberman, P M, Hardwick, J M, Sample, J, Hayward, G S, Hayward, S D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC249228/
https://ncbi.nlm.nih.gov/pubmed/2154599
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