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Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery

The zebrafish is a well-established model organism used in developmental biology. In the last decade, this technology has been extended to the generation of high-value knowledge on safety risks of novel drugs. Indeed, the larval zebrafish appear to combine advantages of whole organism phenotypic ass...

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Detalhes bibliográficos
Main Authors: Barros, T P, Alderton, W K, Reynolds, H M, Roach, A G, Berghmans, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492106/
https://ncbi.nlm.nih.gov/pubmed/18552866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.249
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