A monoclonal antibody to human immunodeficiency virus type 1 which mediates cellular cytotoxicity and neutralization.

Monoclonal antibodies (MAbs) were raised against human immunodeficiency virus type 1 gp120. One MAb, P4/D10, was found to mediate highly efficient antibody-dependent cellular cytotoxicity and virus neutralization. The reactivity was located to a major neutralizing region (amino acids 304 to 323) on...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Broliden, P A, Ljunggren, K, Hinkula, J, Norrby, E, Akerblom, L, Wahren, B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296090/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.936-940.1990
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