Structural rearrangement of integrated hepatitis B virus DNA as well as cellular flanking DNA is present in chronically infected hepatic tissues.

Cellular DNAs from human livers chronically infected with hepatitis B virus (HBV) were analyzed by Southern blot hybridization for the presence of integrated HBV DNA. In 15 of 16 chronically infected hepatic tissues, random HBV DNA integration was evident. By molecular cloning and structural analyse...

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Pubblicato in:	J Virol
Autori principali:	Takada, S, Gotoh, Y, Hayashi, S, Yoshida, M, Koike, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.822-828.1990
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