Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact.

We examined the effects of mouse mammary tumor virus integration on the multiple RNA transcripts expressed from the int-2 proto-oncogene in virally induced breast tumors. Proviral insertion either upstream or downstream of the gene could simultaneously activate transcription from three dissimilar in...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Dickson, C, Smith, R, Brookes, S, Peters, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.784-793.1990
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