Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact.
We examined the effects of mouse mammary tumor virus integration on the multiple RNA transcripts expressed from the int-2 proto-oncogene in virally induced breast tumors. Proviral insertion either upstream or downstream of the gene could simultaneously activate transcription from three dissimilar in...
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| Pubblicato in: | J Virol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1990
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153243/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.784-793.1990 |
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