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Contribution of Reactive Oxygen Species to para-Aminophenol Toxicity in LLC-PK(1) Cells

Para-aminophenol (PAP) causes nephrotoxicity by biochemical mechanisms that have not been fully elucidated. PAP can undergo enzymatic or non-enzymatic oxidation to form reactive intermediates. Using modulators of reactive oxygen species (ROS), the role of ROS in PAP toxicity in LLC-PK(1) cells was i...

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Detalhes bibliográficos
Main Authors: Foreman, Brooke D., Tarloff, Joan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491647/
https://ncbi.nlm.nih.gov/pubmed/18396305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.02.014
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