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Very high frequency of reversion to guanidine resistance in clonal pools of guanidine-dependent type 1 poliovirus.

We have carefully examined the frequency of guanidine-resistant revertants in six different clonal pools of guanidine-dependent mutants of type 1 poliovirus. The mutation frequency was (6.5 +/- 6.3) x 10(-4) (with all amino acid substitutions occurring at position 227). The minimal corrected base su...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: de la Torre, J C, Wimmer, E, Holland, J J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249158/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.664-671.1990
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