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P68 RNA Helicase (DDX5) Alters Activity of Cis- and Trans-Acting Factors of the Alternative Splicing of H-Ras

BACKGROUND: H-Ras pre-mRNA undergoes an alternative splicing process to render two proteins, namely p21 H-Ras and p19 H-Ras, due to either the exclusion or inclusion of the alternative intron D exon (IDX), respectively. p68 RNA helicase (p68) is known to reduce IDX inclusion. PRINCIPAL FINDINGS: Her...

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Detalhes bibliográficos
Main Authors: Camats, Maria, Guil, Sonia, Kokolo, Mariette, Bach-Elias, Montse
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491553/
https://ncbi.nlm.nih.gov/pubmed/18698352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002926
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