Synthesis of hepadnavirus particles that contain replication-defective duck hepatitis B virus genomes in cultured HuH7 cells.

To evaluate the possibility of producing transducible replication-defective hepadnaviruses, cloned mutant duck hepatitis B virus genomes were tested both for virus antigen production and viral DNA synthesis following transfection into the human hepatoma cell line HuH7. Deletion of a cis-acting 12-nu...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Horwich, A L, Furtak, K, Pugh, J, Summers, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.642-650.1990
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