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Synthesis of hepadnavirus particles that contain replication-defective duck hepatitis B virus genomes in cultured HuH7 cells.

To evaluate the possibility of producing transducible replication-defective hepadnaviruses, cloned mutant duck hepatitis B virus genomes were tested both for virus antigen production and viral DNA synthesis following transfection into the human hepatoma cell line HuH7. Deletion of a cis-acting 12-nu...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Horwich, A L, Furtak, K, Pugh, J, Summers, J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.642-650.1990
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