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A-to-I RNA editing alters less-conserved residues of highly conserved coding regions: Implications for dual functions in evolution

The molecular mechanism and physiological function of recoding by A-to-I RNA editing is well known, but its evolutionary significance remains a mystery. We analyzed the RNA editing of the Kv2 K(+) channel from different insects spanning more than 300 million years of evolution: Drosophila melanogast...

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Hlavní autoři: Yang, Yun, Lv, Jianning, Gui, Bin, Yin, Heng, Wu, Xiaojie, Zhang, Yaozhou, Jin, Yongfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491475/
https://ncbi.nlm.nih.gov/pubmed/18567816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1063708
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