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Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

Inflammation plays a critical role in the development of cardiovascular diseases. Infiltration of leukocytes to sites of injury requires their exit from the blood and migration across basement membrane; this process has been postulated to require remodeling of the ECM. Plasminogen (Plg) is a proteas...

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Bibliographic Details
Main Authors: Gong, Yanqing, Hart, Erika, Shchurin, Aleksey, Hoover-Plow, Jane
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491456/
https://ncbi.nlm.nih.gov/pubmed/18677407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32750
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