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FDG uptake, a surrogate of tumour hypoxia?

INTRODUCTION: Tumour hyperglycolysis is driven by activation of hypoxia-inducible factor-1 (HIF-1) through tumour hypoxia. Accordingly, the degree of 2-fluro-2-deoxy-d-glucose (FDG) uptake by tumours might indirectly reflect the level of hypoxia, obviating the need for more specific radiopharmaceuti...

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Detalhes bibliográficos
Main Authors: Dierckx, Rudi Andre, Van de Wiele, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491423/
https://ncbi.nlm.nih.gov/pubmed/18509637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-008-0758-5
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