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Chloroquine resistance of Plasmodium berghei: biochemical basis and countermeasures

Microsomal monooxygenases, enzymes that metabolize xenobiotics, may be responsible for the chloroquine resistance of malarial parasites. Plasmodium cells contain cytochrome P-450 and exhibit aryl hydrocarbon hydroxylase and aminopyrine N-dimethylase activity, two monooxygenases that inactivate chlor...

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Bibliografski detalji
Glavni autori: Salganik, R. I., Pankova, T. G., Chekhonadskikh, T. V., Igonina, T. M.
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491009/
https://ncbi.nlm.nih.gov/pubmed/3117393
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