A dileucine motif in the C terminus of the β(2)-adrenergic receptor is involved in receptor internalization

The cytoplasmic C terminus of the β(2)-adrenergic receptor and many other G protein-coupled receptors contains a dileucine sequence that has been implicated in endosome/lysosome targeting of diverse proteins. In the present study, we provide evidence for an essential role of this motif in the agonis...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gabilondo, Ane M., Hegler, Jutta, Krasel, Cornelius, Boivin-Jahns, Valerie, Hein, Lutz, Lohse, Martin J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12285
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