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Conditional poliovirus mutants made by random deletion mutagenesis of infectious cDNA.

Small deletions were introduced into DNA plasmids bearing cDNA copies of Mahoney type 1 poliovirus RNA. The procedure used was similar to that of P. Hearing and T. Shenk (J. Mol. Biol. 167:809-822, 1983), with modifications designed to introduce only one lesion randomly into each DNA molecule. Metho...

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Bibliografiske detaljer
Main Authors: Kirkegaard, K, Nelsen, B
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC249081/
https://ncbi.nlm.nih.gov/pubmed/2152811
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